Tug1 lncrna

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August undefined, 2024

WebLncRNA‑TUG1在制备调控牙周膜干细胞的干性维持能力的药物中的应用,山东大学,202410562422.1,发明公布,本发明公开了LncRNA‑TUG1在制备调控牙周膜干细胞的干 … WebOct 17, 2016 · Like most other lncRNAs, the functional role of TUG1 has been poorly understood. TUG1 expression is increased in most cancer types, and knockdown of TUG1 in cultured cancer cells has been shown to suppress cell proliferation, invasion, and colony formation ( 15 ).

Long noncoding RNA TUG1 is downregulated in non-small cell …

WebJan 29, 2024 · LncRNA TUG1 reduces inflammation and enhances insulin sensitivity in white adipose tissue by regulating miR-204/SIRT1 axis in obesity mice. LncRNA TUG1 competitively binds to miR-340 to accelerate myocardial ischemia-reperfusion injury. The Tug1 lncRNA locus is essential for male fertility. WebMar 28, 2024 · LncRNA TUG1 promotes neuronal apoptosis through inhibition of mitophagy. TUG1 decreased SIRT1 expression by promoting FBXW7-mediated SIRT1 ubiquitination. FBXW7/SIRT1 axis mediated the effect of TUG1 on OGD/R-induced neuronal apoptosis by regulating mitophagy. Introduction flintshire archives hawarden

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WebJun 1, 2024 · Long noncoding RNA (lncRNA) is a type of non-coding RNA that is at least 200 nucleotides in length and does not encode any protein (Zhang et al. 2024 ). In recent years, lncRNA has been found to have the function of trapping microRNA (miRNA) and regulating gene functions by reducing the expression level of some miRNAs (Guo et al. … WebLncRNA-TUG1在制备调控牙周膜干细胞的干性维持能力的药物中的应用,山东大学,202410562422.1,发明授权,本发明公开了LncRNA‑TUG1在制备调控牙周膜干细胞的干 … WebJan 20, 2016 · The LncRNA taurine up-regulated gene1 (LncRNA TUG1), which is highly conserved in mammals, was originally detected in a genomic screen in taurine-treated mouse retinal cells. It was found that knockdown of TUG1 with RNA interference resulted in malformed or nonexistent outer segments of transfected photoreceptors through … flintshire ash dieback plan

55000 - Gene ResultTUG1 taurine up-regulated 1 [ (human)]

WebApr 10, 2024 · lncRNA TUG1 promotes proliferation and differentiation of osteoblasts by regulating the miR-545-3p/CNR2 axis. Long noncoding RNA TUG1 promotes osteogenic … greater regional medical center mt ayrWebThe lncRNA taurine-upregulated gene 1 (TUG1) directly binds to polycomb repressive complex 2 (PRC2) or PRC1 represses gene expression, and has been reported to participate in oncogenic processes. 11,12 TUG1 acts as a key regulator of drug resistance by sponging miRNAs and involved in the control of some cancer-related genes. 13–15 greater renaissance baptist church saginaw

"WebFeb 8, 2024 · Various lncRNAs are involved in this process. For instance, TUG1 can inhibit miR-132-3p expression, thereby increasing SOX4 expression. This decreases caspase-3 activity, eventually inhibiting... " - Tug1 lncrna

Tug1 lncrna

lncRNA TUG1 as a ceRNA promotes PM exposure-induced …

WebAug 22, 2024 · LncRNA Tug1 Contributes Post-stroke NLRP3 Inflammasome-Dependent Pyroptosis via miR-145a-5p/Tlr4 Axis Pyroptosis, a type of programmed cell death illuminated by inflammasomes and active caspases, is implicated in … WebApr 8, 2024 · Studies have reported that lncRNA taurine-upregulated gene 1 (TUG1) mediates the progression of osteosarcoma and bladder cancer by stimulating cell proliferation [129,130]. TUG1 was expressed at higher levels in PC tissues than in paracarcinoma tissues and could enhance viability, migration, and GEM resistance …

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Web本发明通过研究LncRNA‑TUG1调控PDLSCs成骨分化和组织再生的体内外实验，LncRNA‑TUG1在牙周膜干细胞成骨分化和组织再生过程中起了重要的调控作用，LncRNA‑TUG1可作为组织再生治疗的潜在靶点，推动开发出新的关于LncRNA‑TUG1相关药物或因子，并最终将其运用到再生 ... WebThe lncRNA taurine-upregulated gene 1 (TUG1) is known to serve a role as an oncogene in the development of a number of human malignancies. However, the functionality of …

WebFeb 22, 2024 · LncRNA TUG1, along with other lncRNAs, have been shown to regulate the cell cycle, which is specifically increased during aging [ 49 ]. LncRNA TUG1 has also been shown to disrupt the expression of the Homeobox (HOX) gene family, such as HOXB7, thereby leading to an aging phenotype [ 50 ]. WebNov 8, 2024 · Similarly, the lncRNA TUG1 is aberrantly expressed in many cancers ( Kondo et al., 2024 ). TUG1 is significantly upregulated in PDAC tissues, competitively working as a sponge to miR-382, and upregulating the expression of enhancer of zeste homolog 2 (EZH2), which is targeted by miR-382.

WebJan 29, 2024 · 7.1 kb long lncRNA taurine-upregulated gene 1 (TUG-1) is located on chromosome 22q12. TUG-1 is aberrantly expressed in cancer and has been involved in the progression of various types of tumors: hepatocellular carcinoma, non-small-cell lung cancer (NSCLC), cancer of the bladder, and cancer of the colon [ 13 – 15 ]. WebJul 18, 2024 · lncRNA TUG1 expression is increased in human skeletal muscle in response to a single bout of aerobic exercise. Gene expression of A TUG1, B PPARGC1A and C TFAM measured by RT-qPCR from muscle ( vastus lateralis) biopsy samples before (Pre Ex), immediately (Post 0 h) and 3 h after (Post 3 h) a 60-min bout of cycling exercise at …

WebApr 8, 2024 · Long and et al. linked the modulation of mitochondrial metabolism to the lncRNA TUG1 . Specifically, they observed that TUG1 was linked to mitochondrial bioenergetics by recruitment of PGC-1α (Peroxisome proliferator-activated receptor-γ Coactivator-1 α) to its promoter. Transgenic mice that overexpressed TUG1 in podocytes …

WebOct 15, 2024 · Background Diabetes is associated with the dysfunction of endothelial progenitor cells (EPCs), characterized as impaired angiogenesis, a phenomenon thought to be involved in the development of diabetic foot. lncRNA plays an essential role in microvascular dysfunction and signaling pathways in patients with diabetes. lncRNA … greater reno church of christWebJun 3, 2024 · On a subcellular level, molecular activities of TUG1 lncRNA were pinpointed to the nucleus where it was shown to suppress cell-cycle-related gene expression by … greater remove curse 5eWebTUG1 lncRNA is involved in various aspects of tumor progression, including cell proliferation, migration, and invasion. Downregulation of TUG1 by therapeutic agents may be valuable for the prevention of EOC; thus, our findings indicate that knockdown of TUG1 is a potential novel therapeutic approach for EOC. greater remnant churchWebTUG1: a pivotal oncogenic long non-coding RNA of human cancers. Long non-coding RNAs (lncRNAs) are a group greater than 200 nucleotides in length. An increasing number of … flintshire buckley white bedside cabinetWebFeb 20, 2015 · VA Directive 6518 4 f. The VA shall identify and designate as “common” all information that is used across multiple Administrations and staff offices to serve VA … flintshire bus timetable route 29WebAug 15, 2024 · lncRNA TUG1 as a ceRNA promotes PM exposure-induced airway hyper-reactivity With the increased appreciation for the significance of noncoding RNAs … greater reno areaWebMar 14, 2024 · LncRNAs are non-coding RNAs with a transcript length > 200 nucleotides. They are transcribed by RNA polymerase II, capped, spliced, and polyadenylated. They are expressed in a tissue- and... greater reno community ice skating assoc