Sftpb protein function

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August undefined, 2024

Web1 Apr 2024 · We found that only one HDL protein—SFTPB (pulmonary surfactant protein B)—predicted incident CVD in all the models tested. In a fully adjusted model that controlled for lipids and other risk factors, the hazard ratio was 2.17 per SD increase of SFTPB (95% confidence interval, 1.12–4.21, P Supplementary key words SFTPB HDL proteomics … WebSFTPB. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. …

SFTPB Gene - GeneCards PSPB Protein PSPB Antibody

WebSurfactant protein B (SFTPB) This gene codes for proteins that assist breathing and is not involved in the regulation of the cell cycle. P53 tumor suppressor (TP53) This gene codes for a protein that is located in the mitochondria and in the nucleolus. This protein is involved with cell cycle checkpoints. marsh highfield clockmaker

SFTPB — Early Detection Research Network

Web[9] SFTPB, together with other proteins and phospholipids, creates a barrier on the surface of the alveoli that prevents damage to the alveoli during breathing and is largely generated and secreted by type II cells[10]. The SFTPB gene has been linked to pulmonary illnesses and lung function in earlier research. Web29 Mar 2024 · Summary This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis … Web22 Jan 2015 · Plasma pro-surfactant protein B (pro-SFTPB) levels have recently been shown to predict the development of lung cancer in current and ex-smokers, but the ability of pro-SFTPB to predict... marsh hill grits

Genetic disorders of surfactant protein dysfunction: when to …

Pulmonary surfactant protein B carried by HDL predicts incident …

Websftpb. sections. tissue brain single cell type tissue cell type pathology disease immune cell blood protein subcellular ... contact news. news articles press room learn. dictionary protein classes protein evidence methods educational videos data. downloadable data publication data release history sars-cov-2 help. antibody validation ... WebSFTPB is part of cluster 19 Lung - Lung function with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects … marsh hen mill cornbread recipeWebNX_P07988 - SFTPB - Pulmonary surfactant-associated protein B - Function. Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension … marsh hen mill carolina gold

"WebDescription. Surfactant dysfunction is a lung disorder that causes breathing problems. This condition results from abnormalities in the composition or function of surfactant, a … " - Sftpb protein function

Sftpb protein function

SFTPB Human Protein Surfactant Protein B ProSpecBio

WebThe hydrophobic surfactant proteins B and C are essential for lung function and pulmonary homeostasis after birth. These proteins enhance the spreading, adsorption, and stability … WebSurfactant protein dysfunction syndromes are highly variable in their onset and presentation, and are dependent on the genes involved and environmental factors. This heterogeneous …

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WebPlasma pro-surfactant protein B (pro-SFTPB) levels have recently been shown to predict the development of lung cancer in current and ex-smokers, but the ability of pro-SFTPB to predict measures of chronic obstructive pulmonary disease (COPD) severity is unknown. We evaluated the performance characte … Web20:Airway & Pancreas - Proteolysis41:Alveolar cells - Lung function63:Astrocytes - Nervous system maintenance62:B-cells - B-cell activation70:Basal prostatic cells - Lipid …

WebSFTPB. This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. WebSFTPB. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.

WebThe SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. … WebThis gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for l ung function and homeostasis after birth. Pulmonary …

Web14 Mar 2024 · We found that only one HDL protein—SFTPB (pulmonary surfactant protein B)—predicted incident CVD in all the models tested. In a fully adjusted model that controlled for lipids and other risk factors, the hazard ratio was 2.17 per SD increase of SFTPB (95% confidence interval, 1.12–4.21, P = 0.022).

WebTransfection of A549 cells with NKX2-1 expression vectors demonstrated decreased stimulation of SFTPB and SFTPC expression by mutant proteins compared with that of WT. Conclusion: Disruption of transcriptional activation of surfactant protein genes by these DNA-binding domain mutations is a plausible biological mechanism for disruption of … marsh hill birminghamWebThe SFTPB gene provides instructions for making a protein called surfactant protein-B (SP-B). This protein is one of four proteins (each produced from a different gene) in … marsh hen mill grits recipeWebSFTPB is an amphipathic surfactant protein critical for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which consist of plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. Pulmonary surfactant-associated proteins support alveolar stability by ... marsh highland apartmentsWebSFTPB, or pulmonary-associated surfactant protein B, is an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant-associated … marsh hensWeb8 Feb 2024 · Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific NAMPT knockdown. - Abstract - Europe PMC Europe PMC is an archive of life sciences journal literature. Europe PMC Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific … marsh hill homertonWebPulmonary Genomics. “A COMPREHENSIVE TEST PANEL TO EVALUATE LUNG FUNCTION”. Genetic pulmonary diseases are respiratory conditions commonly passed down in the genes of generational relations. Some diseases are frequently found in the population and can be managed through drug and lifestyle therapies. An excellent example of this would be … marsh high point nc hoosier cabinetWeb2 Oct 2024 · Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). We hypothesized that single nucleotide polymorphisms (SNPs) within the SP genes associate … marsh honey ettrick