WebNov 30, 2024 · Liu, Q. et al. Glycogen accumulation and phase separation drives liver tumor initiation. Cell 184 , 5559–5576 (2024) Article CAS Google Scholar WebSummary. Glycogen storage disease type 2, also known as Pompe disease or acid maltase deficiency disease, is an inherited metabolic disorder. Muscle weakness is usually the main symptom. Glycogen storage disease type 2 is caused by genetic changes (pathogenic variants) in the GAA gene which have instructions to produce the enzyme …
Glycogen controls Caenorhabditis elegans lifespan and
WebJan 12, 2024 · Liu, Li, Zhang, Xiao, Zhang, and colleagues investigated the role of glycogen in tumor initiation in the liver, finding that there is an accumulation of glycogen in early-stage hepatic tumors. Longitudinal analysis of glycogen content at different stages of tumor development indicated that these elevated amounts at early tumor stages are then ... WebJul 14, 2024 · High glucose also led to cell glycogen accumulation by increasing the glucose uptake ability and affecting the mRNA expressions of glycogen synthase and glycogen phosphorylase. Meanwhile, it activated AMP-activated protein kinase (AMPK), inhibited the activity of mammalian target of rapamycin (mTOR) signalling pathway and … medication headache breastfeeding
Glycogen metabolism is dispensable for tumour progression in …
WebJun 9, 2024 · Bacterial growth and yeast sporulation have also been associated with glycogen accumulation. Glycogen Metabolism Glycogen homeostasis is a highly regulated process that allows the body to store … WebThe effects on levels of glycogen phosphorylase, the resultant effects on flux through the glycolytic pathway, and the consequences of these changes on adenylate (ATP, ADP, and AMP) levels in rat liver during a 24-hr period of cold hypoxia were studied. ... Total lactate accumulation in control livers (flushed and stored with a histidine ... Web2 days ago · In mosquitoes subjected to light pollution, long-day mosquitoes accumulated little glycogen, while the short-day mosquitoes showed an increase in glycogen accumulation. Researchers' findings suggest light pollution causes mosquitoes to ward off diapause, possibly by interfering with signals from their circadian clock. medication handover template